Wee Beasties in Nature 432, 2 December 2004, 557
London: Macmillan, 2004. 1st Edition. FIRST EDITION, ORIGINAL PRINTED WRAPS, OF A WELL-KNOWN 2004 ESSAY BY THE NOBEL PRIZE WINNING ENGLISH GENETICIST, PAUL NURSE. The essay presents both a personal and scientific turning point, relating to “how a tiny observation turned out to have a controlling influence” on his 1974 research. Nurse’s research centered on the fission yeast Schizosaccharomyces pombe, where he notably discovered the Wee1 gene, a key player in controlling cell division. The phrase "wee beasties" is a lighthearted nod to these tiny yeast cells, emphasizing their minuscule size.
“Paul Nurse has helped to show how the cell cycle is controlled. Through studies of yeast in the mid-1970s, he was able to show that a special gene plays a decisive role in several of the cell cycle's phases. In 1987 he identified a corresponding human gene” (Noble Prize). And in 2001, Nurse, together with Leland Hartwell and Tim Hunt, received the 2001 Nobel Prize in Physiology or Medicine for their groundbreaking work identifying crucial regulators of the cell cycle – work that has contributed significantly to a revolution in cell biology and cancer research.
NOTE: A number of other influential papers are included. Item #1124
CONDITION & DETAILS: London: Macmillan. Original wraps. 4to. (11 x 8.25 inches; 275 x 206mm. Mailing label on front wrap; very slight rubbing at the edges. The wraps are tight and solid. Bright and clean inside and out. Near fine.
Price: $125.00