1955. 1st Edition. FIRST EDITION WITH ORIGINAL WRAPS BOUND IN of the groundbreaking theoretical paper by Niels K. Jerne describing his theory of antibody formulation.
In 1984 when the Nobel Prize Committee awarded Jerne for his work in Physiology and Medicine, they did so noting that his "view of the nature of the immune system constitutes the basis for modern immunology" (Nobel Prize Committee) "Jerne's "natural-selection theory regarding antibody formation breaks with old views on the immune response and is a starting point of modern cellular immunology" (Nobel Prize Press Release, nobelprize)."
Jerne "proposed that a broad range of specificities of antibodies were released into the blood spontaneously and that antibodies were subject to a replicative drive following their binding to antigen." In order to remain consistent with data indicating a cellular origin of antibody production, he postulated that on binding antigen, antibodies were shuttled to the appropriate cells for reproduction (Pollard, Antibodies and autoimmunity, 46)." Jerne shared the 1984 Nobel Prize in Physiology and Medicine "for theories concerning the specificity in development and control of the immune system. Item #168
CONDITION & DETAILS: Annual volume with original wraps included. Ex-libris volume with library stickers on spine and rear cover, and bookplate inside front cover; each of the front wraps has a small stamp on it. Bound in maroon cloth, gilt-lettered at the spine. Tightly and solidly bound. Bright and very clean throughout. Very good condition.